Tirzepatide Dosing Schedule
| Tirzepatide Titration Schedule | |||||||
|---|---|---|---|---|---|---|---|
| Note: Depending on individual patient needs and clinical judgment, tirzepatide may be compounded with either Vitamin B12 (methylcobalamin) or Glycine. Both formulations follow the same titration protocol based on dosage and treatment duration. | |||||||
| Compound | Strength | Dose | Units | Frequency | Vial Size | Supply Duration | Dosing Weeks |
| Tirzepatide-B12 | 8.5mg-500mcg/ml | 2.125mg | 25 units | sq qw | 1ml | 4 weeks | Weeks 1–4 |
| Tirzepatide-B12 | 8.5mg-500mcg/ml | 4.25mg | 50 units | sq qw | 2ml | 4 weeks | Weeks 5–8 |
| Tirzepatide-B12 | 8.5mg-500mcg/ml | 6.375mg | 75 units | sq qw | 3ml | 4 weeks | Weeks 9–12 |
| Tirzepatide-B12 | 17mg-500mcg/ml | 8.5mg | 50 units | sq qw | 2ml | 4 weeks | Weeks 13–16 |
| Tirzepatide-B12 | 17mg-500mcg/ml | 11mg | 64 units | sq qw | 3ml | 4 weeks | Weeks 17–20 |
| Tirzepatide-B12 | 17mg-500mcg/ml | 13.5mg | 80 units | sq qw | 3.5ml | 4 weeks | Weeks 21–24 |
| Tirzepatide-B12 | 17mg-500mcg/ml | 17mg | 100 units | sq qw | 4ml | 4 weeks | Weeks 25 through duration of treatment |
| Tirzepatide/Glycine | 8.5mg-5mg/ml | 2.125mg | 25 units | subq qw | 1ml | 4 weeks | Weeks 1–4 |
| Tirzepatide/Glycine | 8.5mg-5mg/ml | 4.25mg | 50 units | subq qw | 2ml | 4 weeks | Weeks 5–8 |
| Tirzepatide/Glycine | 8.5mg-5mg/ml | 6.375mg | 75 units | subq qw | 3ml | 4 weeks | Weeks 9–12 |
| Tirzepatide/Glycine | 17mg-5mg/ml | 8.5mg | 50 units | subq qw | 2ml | 4 weeks | Weeks 13–16 |
| Tirzepatide/Glycine | 17mg-5mg/ml | 11mg | 64 units | subq qw | 3ml | 4 weeks | Weeks 17–20 |
| Tirzepatide/Glycine | 17mg-5mg/ml | 13.5mg | 80 units | subq qw | 3.5ml | 4 weeks | Weeks 21–24 |
| Tirzepatide/Glycine | 17mg-5mg/ml | 17mg | 100 units | subq qw | 4ml | 4 weeks | Weeks 25 through duration of treatment |
